Dr. Brent Johnston’s research focuses on immune cell development, homing, and activation. We are currently studying the regulation of autoimmunity and anti-tumour immune responses by natural killer T (NKT) cells, a subset of leukocytes that bridge the innate and adaptive immune systems.
Read MoreMy research investigates the intersection of host age and previous infection in the context of influenza infection and vaccination. I use animal models, in vitro systems, and patient samples to obtain a picture of disease and its mechanisms. I recently discovered that lactating mammary glands are susceptible to influenza infection.
Read MoreKelvin and his research team a large part of their research in southeast Asia, where several new viruses have emerged in recent years: the severe acute respiratory syndrome (SARS) coronavirus, the H5N1 strain of avian influenza (bird flu) and the more recent H7N9 strain that can cause human infections. Being able to characterize a newly emerging influenza virus early is key to understanding whether it has the ability to spread from person to person, cause severe disease or cause a pandemic.
Read MoreWe study virus-host interactions with a focus on intrinsic cell defense mechanisms and their subversion by influenza viruses. Another area of interest in the lab is the biology of stress granules – cytoplasmic foci of messenger RNA-protein complexes that form in response to various types of stress, including viral infections
Read MoreThe focus of Dr. Langille's research is to better understand human-microbial interactions and how that can be used to improve human health. This includes leveraging novel genomic technologies and developing improved bioinformatic methods to process and integrate multi-omic data to aid in biological interpretation. These discoveries will hopefully lead to novel applications for diagnosis, therapeutics, and precision medicine.
Read MoreDr. Langley is a pediatric infectious disease physician in the Department of Pediatrics and is cross-appointed in the Department of Community Health and Epidemiology in the Faculty of Medicine. She is based at the IWK Health Centre and the Canadian Center for Vaccinology. She conducts studies on the prevention of infectious diseases using vaccines, from phase 1 (first in humans) through to efficacy trials (phase 3) and post-marketing studies of how well vaccines work when they are used in immunization programs (phase 4). These studies are done with collaborators in public health, industry, universities, and non-governmental organizations. Dr. Langley has a particular interest in prevention of respiratory infections such as Respiratory Syncytial Virus and influenza. Her work also focuses on vaccine policy and evidence-based decision making in immunization programs.
Read MoreThe primary research interests are in the use of commensal bacteria as live oral vaccine vehicles, host-bacteria interactions, and bacterial physiology. Other interests include pathogenesis of and immunity to oral bacteria.
Read MoreDr Légaré is the Head of Cardiac Surgery at the New Brunswick Heart Centre and Professor of Surgery at Dalhousie University Medicine New Brunswick located in Saint John New Brunswick.
Read MoreProfessor Lehmann’s research interests include the immune consequences of local and systemic inflammation (e.g., sepsis, stroke), intravital imaging of the microcirculation in animal models and clinical studies, and the development of new pharmacological approaches for inflammation and infection.
Read MoreDr. Makrigiannis’ research focus is the innate immune system, and in particular Natural Killer (NK) cell recognition of virally-infected or cancerous cells via the polymorphic Ly49 family of class I MHC receptors and the related NKR-P1 receptor family, in order to understand the contribution of NK cell receptors to diseases for translation into clinical therapies.
Read MoreDr. Marshall has a long term interest in the biology and function of mast cells in host defence and disease. This includes study of mast cells in models of viral infection, cancer and allergic disease such as asthma and food allergy. Her work often involves multidisciplinary teams of scientists and multiple research trainees.
Read MoreOur research is focused on innate host antiviral defenses and the viral countermeasures that have evolved to subvert these defenses. We study two viruses, influenza virus and a cancer-causing herpesvirus known as KSHV.
Read MoreUsing animal models of rheumatoid arthritis, osteoarthritis and joint injury, Dr. McDougall's laboratory employs an integrative approach to examine the role of nerves in controlling joint inflammation and pain.
Read MoreDr. McNeil is professor of medicine and clinical scholar at Dalhousie University. She is also the division head / service chief for the Division of Infectious Diseases at the Nova Scotia Health Authority and research director of the Division of Infectious Diseases. Dr. McNeil is an accomplished researcher who completed internal medicine training at Dalhousie, followed by a fellowship in infectious diseases at the University of Michigan School of Medicine.
Read MoreDr. Sharon Oldford is an immunologist who works with Dr. Barrett to coordinate SAIL’s basic science research projects. Her current research interests include investigating the effects of chronic viral infection on immune phenotype and functional changes and experimental models of immunologic aging.
Read MoreMy research involves the molecular biology of measles, canine distemper, hepatitis C, and hepatitis B viruses. We are particularly interested in virus-host cell receptor interactions. Many of these receptors have been found to be highly up-regulated on cancer cells and can be targeted for therapy by recombinant oncolytic viruses.
Read MoreMy research interests are in the applicaton of Statistics to science and medicine.
Read MoreThe research interests of Immunovaccine include the development of a patented DepoVaxTMvaccine adjuvanting platform and vaccines - candidates for use in cancer immunotherapy, infectious disease and animal health.
Read MoreDr. Steenbeek is an Epidemiologist with expertise on Aboriginal sexual health, sexually transmitted infections, community based research and quantitative research methodology. Dr. Steenbeek received her PhD and Masters from UBC and her BScN from McMaster. She holds an active nursing practice at both the local ER department and in the north. Dr. Steenbeek has an appointment in Pediatrics at the IWK and is a member of the Health Policy & Knowledge Translation at the Canadian Centre of Vaccinology.
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