Infection — Our Team "Blog" — Dal I3V

Posts tagged Infection

Lisa Barrett

Lisa Barrett

The Senescence, Aging, Infection and Immunity (SAIL) laboratory studies immune responses in chronic and persistent viral infections (HIV, CMV, HCV); the role of chronic viral infection in chronologic and immunologic aging; interactions between innate and adaptive immunity in chronic viral infection and the modulation of the immune response to generate therapeutic and prophylactic vaccines in persistent viral infections. Clinically Dr. Barrett is also interested in treating viral infections in underserved and incarcerated populations.

Guest UserMay 2, 2019Infection, Immunity, Inflammation, Vaccinology

Jeanette Boudreau

Jeanette Boudreau

We investigate how human natural killer cell immunogenetics program immune responsiveness to cancer and infectious diseases. We use bioinformatics, humanized in vivo models, cell-signal analysis, and highly-parametric flow cytometry to understand how genetic variation creates diversity in human immune potentials. Our interdisciplinary and collaborative work aims to translate research findings into precision therapies.

Guest UserMay 2, 2019Infection, Immunity, Inflammation

Francesca Di Cara

Francesca Di Cara

Our research relies primarily on the use of Drosophila, a genetically amenable model system, to elucidate the previously unexplored role of peroxisomes as signaling platforms in the innate immune response. We demonstrated the peroxisome direct involvement in immune defense, with evidence of peroxisome requirements in phagocytic pathogen clearance and innate immune signaling in immune responsive tissue in flies and mammals. Peroxisomes are essential metabolic organelles present in every eukaryotic cell.

Guest UserMay 2, 2019Infection, Immunity, Inflammation

Roy Duncan

Roy Duncan

Dr. Duncan’s research group discovered the reovirus fusion-associated small transmembrane (FAST) proteins, a novel family of virus-encoded fusogens that mediate cell-cell membrane fusion. His interests are focused on biochemical and biophysical analysis of the FAST proteins, cellular pathways involved in cell-cell fusion, and factors that affect actin dynamics during membrane fusion and cell migration.

Guest UserMay 2, 2019Infection, Vaccinology

Shashi Gujar

Shashi Gujar

Dr. Gujar’s research program focuses on molecular and immunological aspects of human health, with special focus on cancer immunotherapies. His multi-disciplinary interests include Oncolytic viruses, Immunology and immunotherapies, Epitope discovery, Cellular biology and metabolism, Applied immunomics and Proteo-immuno-metabolomics.

Guest UserMay 2, 2019Infection, Immunity, Inflammation

Scott Halperin

Scott Halperin

Dr. Halperin’s research focuses on the diagnosis, treatment, and prevention of pertussis and other vaccine-preventable diseases.

Guest UserMay 1, 2019Infection, Immunity, Vaccinology

Todd Hatchette

Todd Hatchette

As the Province’s only Medical Virologist and one of the Directors of Immunology and Virology at the QEII HSC I oversee the running of the clinical virology laboratory. I also oversee the anchor laboratory for the Severe Outcomes Surveillance Project in the PHAC/CIHR Influenza Research Network (PCIRN)

Guest UserApril 29, 2019Infection

Alyson Kelvin

Alyson Kelvin

My research investigates the intersection of host age and previous infection in the context of influenza infection and vaccination. I use animal models, in vitro systems, and patient samples to obtain a picture of disease and its mechanisms. I recently discovered that lactating mammary glands are susceptible to influenza infection.

Guest UserApril 24, 2019Infection, Immunity, Vaccinology

David Kelvin

David Kelvin

Kelvin and his research team a large part of their research in southeast Asia, where several new viruses have emerged in recent years: the severe acute respiratory syndrome (SARS) coronavirus, the H5N1 strain of avian influenza (bird flu) and the more recent H7N9 strain that can cause human infections. Being able to characterize a newly emerging influenza virus early is key to understanding whether it has the ability to spread from person to person, cause severe disease or cause a pandemic.

Guest UserApril 23, 2019Infection, Immunity, Vaccinology

Denys Khaperskyy

Denys Khaperskyy

We study virus-host interactions with a focus on intrinsic cell defense mechanisms and their subversion by influenza viruses. Another area of interest in the lab is the biology of stress granules – cytoplasmic foci of messenger RNA-protein complexes that form in response to various types of stress, including viral infections

Guest UserApril 22, 2019Infection, Vaccinology

Jason LeBlanc

Jason LeBlanc

Guest UserApril 19, 2019Infection, Vaccinology

Song Lee

Song Lee

The primary research interests are in the use of commensal bacteria as live oral vaccine vehicles, host-bacteria interactions, and bacterial physiology. Other interests include pathogenesis of and immunity to oral bacteria.

Guest UserApril 18, 2019Infection, Vaccinology

Andrew Makrigiannis

Andrew Makrigiannis

Dr. Makrigiannis’ research focus is the innate immune system, and in particular Natural Killer (NK) cell recognition of virally-infected or cancerous cells via the polymorphic Ly49 family of class I MHC receptors and the related NKR-P1 receptor family, in order to understand the contribution of NK cell receptors to diseases for translation into clinical therapies.

Guest UserApril 15, 2019Infection, Immunity, Inflammation, Vaccinology

Jean Marshall

Jean Marshall

Dr. Marshall has a long term interest in the biology and function of mast cells in host defence and disease. This includes study of mast cells in models of viral infection, cancer and allergic disease such as asthma and food allergy. Her work often involves multidisciplinary teams of scientists and multiple research trainees.

First BlockGuest UserApril 14, 2019Infection, Immunity, Inflammation

Craig McCormick

Craig McCormick

Our research is focused on innate host antiviral defenses and the viral countermeasures that have evolved to subvert these defenses. We study two viruses, influenza virus and a cancer-causing herpesvirus known as KSHV.

First BlockGuest UserApril 13, 2019Infection, Vaccinology

Shelly McNeil

Shelly McNeil

Dr. McNeil is professor of medicine and clinical scholar at Dalhousie University. She is also the division head / service chief for the Division of Infectious Diseases at the Nova Scotia Health Authority and research director of the Division of Infectious Diseases. Dr. McNeil is an accomplished researcher who completed internal medicine training at Dalhousie, followed by a fellowship in infectious diseases at the University of Michigan School of Medicine.

First BlockGuest UserApril 11, 2019Infection, Vaccinology

Chris Richardson

Chris Richardson

My research involves the molecular biology of measles, canine distemper, hepatitis C, and hepatitis B viruses. We are particularly interested in virus-host cell receptor interactions. Many of these receptors have been found to be highly up-regulated on cancer cells and can be targeted for therapy by recombinant oncolytic viruses.

First BlockGuest UserApril 9, 2019Infection, Vaccinology

Marianne Stanford

Marianne Stanford

The research interests of Immunovaccine include the development of a patented DepoVaxTMvaccine adjuvanting platform and vaccines - candidates for use in cancer immunotherapy, infectious disease and animal health.

First BlockGuest UserApril 7, 2019Infection, Immunity, Vaccinology

Nik Thomas

Nik Thomas

The Thomas Lab investigates molecular mechanisms of disease in significant human pathogens. Projects employ advanced proteomic and genomic approaches, including innovative next generation DNA sequencing technologies. The overall aim is to discover pathogenic strategies that can be targeted for inhibition by new or existing drugs, thereby limiting human disease. The Thomas Lab is a welcoming and inclusive space for all people to explore scientific investigations.

First BlockGuest UserApril 5, 2019Infection

Jun Wang

Jun Wang

Professor Wang’s research interests include (1) understanding the role of regulatory T cells and IL-17/IL-17R axis in host responses to intracellular bacterial infection and cancer; (2) development of prophylactic and/or therapeutic vaccines against infection and cancer.

First BlockGuest UserApril 1, 2019Infection, Immunity, Inflammation, Vaccinology