Morgan Langille
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Research Interests
The focus of Dr. Langille's research is to better understand human-microbial interactions and how that can be used to improve human health. This includes leveraging novel genomic technologies and developing improved bioinformatic methods to process and integrate multi-omic data to aid in biological interpretation. These discoveries will hopefully lead to novel applications for diagnosis, therapeutics, and precision medicine.
Selected Publications
Nearing JT, Connors J, Whitehouse S, Van Limbergen J, MacDonald T, Kulkarni K, Langille MGI (2019) “Infectious complications are associated with alterations in the gut microbiome in pediatric patients with Acute Lymphoblastic Leukemia”., Frontiers in Cellular and Infection Microbiology, 9:28.
Lau WL, Vaziri ND, Nunes A, Comeau AM, Langille MGI, England W, Khazaeli M, Suematsu Y, Phan J, Whiteson K. (2018) “The phosphate binder ferric citrate alters the gut microbiome in rats with chronic kidney disease”., Journal of Pharmacology and Experimental Therapeutics, 367(3):452-460.
Dickson K, Liu S, Zhou J, Langille MGI, Holbein B, Lehmann C. (2018) “Selective sensitivity of the gut microbiome to iron chelators in polybacterial abdominal sepsis”., Medical Hypotheses 120:68-71.
Dranse HJ, Zheng A, Comeau AM, Langille MGI, Zabel BA, Sinal CJ. (2018) “The impact of chemerin or chemokine-like receptor 1 loss on the mouse gut microbiome". , PeerJ 6:e5494.
Nearing JT, Douglas GM, Comeau AM, Langille MGI (2018) “Denoising the Denoisers: an independent evaluation of microbiome sequence error-correction approaches”., PeerJ 6:e5364.
DeClercq V, Langille MGI, Van Limbergen H (2018) “Differences in adiposity and diet quality among individuals with inflammatory bowel disease in Eastern Canada”., PLoS ONE 13(7):e0200580.
Yurgel SN, Douglas GM, Dussault A, Percival D, Langille MGI (2018) “Dissecting community structure in wild blueberry root and soil microbiome”., Frontiers in Microbiology 9, 1187.
Langille MGI (2018) “Exploring linkages between taxonomic and functional profiles of the human microbiome”, mSystems, 3:e00163-17.
Thilakarathna WPDW, Langille MGI, Rupasinghe HPV (2018) “Polyphenol-based prebiotics and synbiotics: potential for cancer chemoprevention”., Current Opinion in Food Science, 20: 51-57.