Brent Johnston

 
B Johnston portrait 1.jpg

External Website:

Brent Johnston Dalhousie University Profile

Research Interests

Dr. Brent Johnston’s research focuses on immune cell development, homing, and activation.  We are currently studying the regulation of autoimmunity and anti-tumour immune responses by natural killer T (NKT) cells, a subset of leukocytes that bridge the innate and adaptive immune systems.

Selected publications

For a complete list of Dr. Brent Johnston's publications, click here.

  • Vienotte L, Gebremeskel S, Johnston B. 2016. CXCL16-positive dendritic cells enhance invariant natural killer T cell-dependent IFN-γ production and tumor control. Oncoimmunology 5:e1160979

  • Gebremeskel S, Slauenwhite D, Johnston B. 2016. Reconstitution models to evaluate natural killer T cell function in tumor control. Immunol. Cell Biol. 94:90-100

  • Slauenwhite D, Johnston B. 2015. Mechanisms regulating NKT cell localization in homeostasis and infection. Front. Immunol. 6:255.

  • Gebremeskel S, Clattenburg DR, Slauenwhite D, Lobert L, Johnston B. 2015. Natural killer T cell activation overcomes immunosuppression to enhance clearance of postsurgical breast cancer metastasis in mice. Oncoimmunology 4:e995562.

  • Slauenwhite D, Gebremeskel S, Doucette CD, Hoskin DW, Johnston B. 2014. Regulation of cytokine polarization and T cell recruitment to inflamed paws in mouse collagen-induced arthritis by the chemokine receptor CXCR6. Arthritis & Rheum. 66:3001-3012.

 
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