Posts tagged Vaccinology
Lisa Barrett

The Senescence, Aging, Infection and Immunity (SAIL) laboratory studies immune responses in chronic and persistent viral infections (HIV, CMV, HCV); the role of chronic viral infection in chronologic and immunologic aging; interactions between innate and adaptive immunity in chronic viral infection and the modulation of the immune response to generate therapeutic and prophylactic vaccines in persistent viral infections. Clinically Dr. Barrett is also interested in treating viral infections in underserved and incarcerated populations.

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Bob Bortolussi

Dr. Bortolussi is a former Vice President of Research of the IWK Health Centre and is Professor Emeritus of Paediatrics at Dalhousie University.  He edited “The Handbook for Clinician Scientists” which is used in many Universities in Canada and as part of the MicroResearch Curriculum. He is a fellow of Canadian Academy of Health Sciences and President of the Global Health Section of the Canadian Paediatric Society. He is presently the editor of Clinical and Investigative Medicine (CIM). 

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Susan Bowles

My research is largely informed by clinical practice, where research questions regarding medication use are identified at the bedside.  My primary research interests involve appropriate medication use in older patients and reducing vaccine-preventable diseases in older populations.

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Roy Duncan

Dr. Duncan’s research group discovered the reovirus fusion-associated small transmembrane (FAST) proteins, a novel family of virus-encoded fusogens that mediate cell-cell membrane fusion. His interests are focused on biochemical and biophysical analysis of the FAST proteins, cellular pathways involved in cell-cell fusion, and factors that affect actin dynamics during membrane fusion and cell migration.

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Janice Graham

Dr. Graham is an anthropologist of science, technology and medicine in the Department of Pediatrics (Infectious Diseases). She studies the cultural, technical and moral tensions in regulating one health. Interested in the moral basis of profit when disease becomes a market opportunity, she works among those who develop, regulate, commercialize, implement and use emerging pharmaceuticals and vaccines to examine their safety and efficacy.

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Donna Halperin

Dr. Halperin’s applied research program focuses on vaccine program implementation and evaluation and health policy research. She has methodological expertise in mixed methods, survey research and grounded theory. Currently she is a co- investigator with the PHAC/CIHR Canadian Immunization Research Network that was established to provide Canada with a national capacity to undertake coordinated, evaluative research to inform public health policy relating to vaccine and vaccination. She is currently a Principal Investigator on a CIHR collaborative study in Nunavut and a Co-Investigator on a Public Health Agency of Canada funded program evaluation in Prince Edward Island.

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Matthew Herder

Professor Herder’s research interests cluster around biomedical innovation policy, with particular focus on intellectual property law and practices connected to the commercialization of scientific research. As part of a three-year research project funded by the Canadian Institutes of Health Research, Professor Herder (Principal Investigator) and a team of interdisciplinary researchers are currently collecting empirical evidence about the inter-relationships between commercialization laws, policies, and practices and emerging health researchers. The team will use the collected empirical evidence to explore a series of normative questions about the ongoing commercialization of academic science.

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Guest UserVaccinology
Jennifer Isenor

Dr. Jennifer Isenor’s research areas include evaluation of the scope of practice of pharmacists, including immunizing and prescribing; assessing the use of drug and health information resources by students and clinicians; and geriatric-related research, with a focus on appropriate medication use, including deprescribing.

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Guest UserVaccinology
Alyson Kelvin

My research investigates the intersection of host age and previous infection in the context of influenza infection and vaccination. I use animal models, in vitro systems, and patient samples to obtain a picture of disease and its mechanisms. I recently discovered that lactating mammary glands are susceptible to influenza infection.

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David Kelvin

Kelvin and his research team a large part of their research in southeast Asia, where several new viruses have emerged in recent years: the severe acute respiratory syndrome (SARS) coronavirus, the H5N1 strain of avian influenza (bird flu) and the more recent H7N9 strain that can cause human infections. Being able to characterize a newly emerging influenza virus early is key to understanding whether it has the ability to spread from person to person, cause severe disease or cause a pandemic.

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Denys Khaperskyy

We study virus-host interactions with a focus on intrinsic cell defense mechanisms and their subversion by influenza viruses. Another area of interest in the lab is the biology of stress granules – cytoplasmic foci of messenger RNA-protein complexes that form in response to various types of stress, including viral infections

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Joanne Langley

Dr. Langley is a pediatric infectious disease physician in the Department of Pediatrics and is cross-appointed in the Department of Community Health and Epidemiology in the Faculty of Medicine. She is based at the IWK Health Centre and the Canadian Center for Vaccinology. She conducts studies on the prevention of infectious diseases using vaccines, from phase 1 (first in humans) through to efficacy trials (phase 3) and post-marketing studies of how well vaccines work when they are used in immunization programs (phase 4). These studies are done with collaborators in public health, industry, universities, and non-governmental organizations. Dr. Langley has a particular interest in prevention of respiratory infections such as Respiratory Syncytial Virus and influenza. Her work also focuses on vaccine policy and evidence-based decision making in immunization programs.

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Guest UserVaccinology
Song Lee

The primary research interests are in the use of commensal bacteria as live oral vaccine vehicles, host-bacteria interactions, and bacterial physiology. Other interests include pathogenesis of and immunity to oral bacteria.

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Andrew Makrigiannis

Dr. Makrigiannis’ research focus is the innate immune system, and in particular Natural Killer (NK) cell recognition of virally-infected or cancerous cells via the polymorphic Ly49 family of class I MHC receptors and the related NKR-P1 receptor family, in order to understand the contribution of NK cell receptors to diseases for translation into clinical therapies.

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Shelly McNeil

Dr. McNeil is professor of medicine and clinical scholar at Dalhousie University. She is also the division head / service chief for the Division of Infectious Diseases at the Nova Scotia Health Authority and research director of the Division of Infectious Diseases. Dr. McNeil is an accomplished researcher who completed internal medicine training at Dalhousie, followed by a fellowship in infectious diseases at the University of Michigan School of Medicine.

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Chris Richardson

My research involves the molecular biology of measles, canine distemper, hepatitis C, and hepatitis B viruses. We are particularly interested in virus-host cell receptor interactions. Many of these receptors have been found to be highly up-regulated on cancer cells and can be targeted for therapy by recombinant oncolytic viruses.

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