Dr. Cheng utilizes systems biology approaches to study the pathogenesis of infectious diseases. His research is relevant to multiple I3V research priorities including antimicrobial resistance, existing and emerging microbial threats, improved diagnostics directly related to infection and immunity, and inflammation. His goal is to identify signalling components in host immunity and bacterial pathogenesis pathways that can be exploited for novel efficient approaches to treat pathogenic infections and enhance host immunity.

Pseudomonas aeruginosa infection and chronic inflammation in Cystic Fibrosis is a major translational research focus for Dr. Cheng.

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